What is the circle of Willis?
The circle of Willis (Circulus arteriosus cerebri) is a vascular structure located at the base of the brain that links the internal carotid and vertebrobasilar arterial systems, supplying consistent blood flow between the brain's anterior and posterior arteries. By forming a collateral pathway, it minimizes the risk of ischemia by redirecting blood flow in the event of arterial blockages. Its typical structure includes the anterior, middle, and posterior cerebral arteries (PCAs) connected by the anterior and posterior communicating (PCOM) arteries. Intracranial aneurysms occur when there is a weakening in one of the blood vessel walls, often in the Circle of Willis, making it susceptible to rupture.
Surrounding the stalk of the pituitary gland, the circle of Willis establishes critical connections between the blood supplies of the forebrain and the hindbrain. This connection bridges the internal carotid and vertebrobasilar systems, compensating for the loss of primitive embryonic vascular links (Krabbe-Hartkamp, 1998; Standring, 2021).
The primary components of the circle of Willis are:
- Anterior cerebral arteries (ACAs): Paired arteries arising from the internal carotid arteries (ICAs).
- Anterior communicating artery (ACOM): A single midline artery connecting the ACAs.
- Internal carotid arteries (ICAs): Branches of the common carotid arteries.
- Posterior cerebral arteries (PCAs): Paired arteries originating from the basilar artery (BA).
- Posterior communicating (PCOM) arteries: Paired arteries linking the ICAs and PCAs.
The anterior circulation comprises the ACAs, ACOM, and middle cerebral arteries (MCAs), which branch from the ICAs. The posterior circulation includes the PCAs, originating from the basilar artery formed by the vertebral arteries. If one of our brain's significant arteries becomes narrow (which slows down blood flow) or there is a blockage (blood flow stops), the Circle of Willis will work to maintain blood circulation by redirecting the blood flow to interconnected branches. This redirection is called collateral blood flow, which means alternative routes will be used if blood flow is disrupted due to an artery being damaged, narrow, or blocked.










