What is a Haptoglobin (HP) Test?
A Haptoglobin Test measures the amounts of haptoglobin in one's blood. Haptoglobin is a protein produced by the liver that commonly binds with “free hemoglobin”, a byproduct of red blood cell destruction, to create a haptoglobin-hemoglobin complex, which is commonly removed from the body as it passes through the liver. Because of its nature, the protein is used as a marker that helps assess the balance between red blood cell destruction and production. Whenever haptoglobin levels drop, it means that the body is eliminating red blood cells faster than the liver can produce it.
Generally, imbalances result from inherited conditions like spleen disorders, myelofibrosis, and cirrhosis, causing the person with said condition to develop hemolytic anemia. Practitioners can detect hemolytic anemia or any other type of anemia through a Haptoglobin Test.
A practitioner will usually request a Haptoglobin Test if the patient exhibits symptoms of hemolytic anemia, such as pale skin, jaundice, severe fatigue, cold hands and feet, upper abdominal pain, lightheadedness, dizziness, arrhythmia, or shortness of breath.










