What is unilateral neglect?
Unilateral neglect, also known as hemispatial neglect, is a neurological condition that typically occurs after damage to one hemisphere of the brain, most commonly the right. This damage leads to an inability to attend to or respond to stimuli on the opposite side of the body. For example, a person with right hemisphere damage might ignore everything on their left side. Unilateral neglect is often associated with stroke but can also result from traumatic brain injury, brain tumors, or other neurological conditions. The severity and impact of unilateral neglect can vary widely among individuals.
Although closely related, it’s essential to distinguish unilateral neglect from unilateral spatial neglect. Spatial neglect specifically refers to a failure to acknowledge or respond to objects or stimuli within the spatial environment on the affected side. Additionally, acute-stage spatial neglect is often observed in the early phases following a stroke and is critical for determining the initial rehabilitation approach.
In contrast, unilateral neglect can encompass a broader range of deficits, including personal neglect (ignoring one side of the body), peripersonal neglect (ignoring the space within arm’s reach), and unilateral spatial orientation neglect. Both conditions significantly impact daily living activities and quality of life. The severity of behavioral neglect, ranging from mild to severe, is also associated with patients' self-awareness of neglect (anosognosia).
Symptoms
The symptoms of unilateral neglect can vary but generally include:
- Difficulty paying attention to one side of the environment.
- Ignoring food on one side of the plate.
- Forgetting to dress or groom one side of the body.
- Bumping into objects or walls on the neglected side.
- Difficulty reading or writing, as the patient may neglect parts of words or sentences.
- In severe cases, complete unawareness of the affected side.
- Abnormal gaze orientation, where the patient may consistently turn their head or eyes away from the neglected side.
Causes
Unilateral neglect can be caused by various neurological conditions, with the most common being:
- Stroke, particularly affecting the right hemisphere.
- Traumatic brain injury.
- Brain tumors.
- Neurodegenerative diseases.
- Infections affecting the brain, such as encephalitis.
- Any condition leading to significant damage to one hemisphere of the brain.
Complications
Unilateral neglect can lead to several complications, impacting both safety and quality of life:
- Increased risk of injury from falls or accidents due to unawareness of the neglected side.
- Difficulties in performing daily activities, leading to decreased independence.
- Social isolation due to challenges in communication and mobility.
- Emotional and psychological distress, including frustration and depression.
- Reduced effectiveness of rehabilitation efforts if the condition is not managed correctly.










