Celiac Disease Test

Discover a reliable way to diagnose Celiac Disease. Gain valuable insights into symptoms, screening, and management strategies. Take control of your health. 


Joshua Napilay
Joshua Napilay
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What is a Celiac Disease Test?

A Celiac Disease Test, also known as celiac panel or celiac serology, is a diagnostic procedure used to determine whether an individual has celiac disease, an autoimmune disorder triggered by the ingestion of gluten. Gluten is a protein found in wheat, barley, and rye, and for people with celiac disease, consuming even small amounts of gluten can lead to severe gastrointestinal and systemic symptoms.

The primary purpose of a Celiac Disease Test is to identify specific antibodies in the blood that are indicative of an immune response to gluten. The three primary antibodies tested for are:

  • Anti-tissue transglutaminase (tTG) antibodies: These antibodies are commonly found in individuals with celiac disease. They are produced when the immune system mistakenly targets the small intestine's lining in response to gluten consumption.
  • Anti-endomysial antibodies (EMA): EMA antibodies are another marker of the autoimmune reaction in celiac disease. They target the endomysium, a connective tissue layer surrounding muscle fibers.
  • Anti-deamidated gliadin peptides (DGP) antibodies: These antibodies target a component of gluten called gliadin. Elevated levels of DGP antibodies can suggest celiac disease.

A blood sample is typically collected from the patient to perform the test. If the initial blood test results suggest celiac disease, a small intestine biopsy may be recommended to confirm the diagnosis. In the biopsy, a small piece of tissue is extracted from the small intestine and examined for characteristic damage caused by the autoimmune response to gluten.

Early and accurate diagnosis of celiac disease is crucial because it allows individuals to adopt a strict gluten-free diet, the only effective treatment for the condition. Celiac disease can lead to serious health complications without proper management, including malnutrition, osteoporosis, and an increased risk of other autoimmune disorders.

Printable Celiac Disease Test

Download this Celiac Disease Test to assess whether your patients have celiac disease.

How Does it Work?


Before undergoing a Celiac Disease Test, individuals should consult a healthcare provider, usually a gastroenterologist or primary care physician. These professionals can assess symptoms, medical history, and family history to determine the need for testing.

Blood Sample Collection

The primary diagnostic step involves drawing a blood sample from the individual. This sample is collected in a vial or test tube.

Laboratory Analysis

The blood sample is sent to a clinical laboratory for analysis. Technicians perform various tests in the lab to detect specific antibodies related to celiac disease. The primary antibodies analyzed include anti-tissue transglutaminase (tTG), anti-endomysial antibodies (EMA), and anti-deamidated gliadin peptides (DGP).

Results Interpretation

The healthcare provider receives the results once the laboratory analysis is complete. They interpret the findings and determine whether the individual has celiac disease based on antibody levels. Positive results may indicate the presence of celiac disease, while negative results suggest its absence.

Additional Testing (if necessary)

In some cases, further testing may be required to confirm the diagnosis. This can include a small intestine biopsy. During a biopsy, a thin, flexible tube with a camera (endoscope) is passed through the mouth and into the small intestine to collect tissue samples. These samples are examined for characteristic damage caused by celiac disease.

Consultation and Diagnosis

After reviewing the test results and, if necessary, biopsy findings, the healthcare provider discusses the diagnosis with the individual. If celiac disease is confirmed, the healthcare provider educates the patient about its management.

For individuals seeking a printable Celiac Disease Test form, it's important to note that healthcare professionals typically administer the test in a clinical setting. Patients usually wait to fill out the test form. Instead, they may be asked to provide personal information and consent for the test documented by healthcare staff.

Celiac Disease Test Example (sample)

A Celiac Disease Test example is an essential document that patients can access in PDF format. This comprehensive document provides a detailed understanding of the testing process, including patient information like name and date of birth, informed consent, and preparation instructions. 

This requires patients to consent, acknowledging the test's purpose, potential risks, and benefits. It also outlines any necessary dietary restrictions or medication adjustments before testing. This helps healthcare providers ensure that the test is performed accurately and safely.

In addition, this includes a checklist for healthcare providers to record blood sample collection, laboratory analysis, and the subsequent diagnosis. This ensures that the entire testing process is recorded and can be referred to in case of discrepancies.

This is vital in ensuring patients are well-informed and prepared for the celiac disease testing procedure. By reading through the sample document, patients can better understand the process and what to expect. This can help reduce anxiety and stress, ensuring a more positive experience for the patient.

Download this Celiac Disease Test Example:

Celiac Disease Test Example (sample)

When Would you use this Test?

The Celiac Disease Test is utilized by healthcare practitioners when specific clinical scenarios or symptoms suggest the possibility of celiac disease. Here are vital situations that prompt the use of this test:

  • Gastrointestinal Symptoms: When patients present with persistent gastrointestinal symptoms such as chronic diarrhea, abdominal pain, bloating, vomiting, or unexplained weight loss, healthcare providers consider the Celiac Disease Test. These symptoms can indicate celiac disease, particularly if they do not respond to standard treatments.
  • Failure to Thrive in Children: In pediatric medicine, the test is employed when children experience growth delays, poor weight gain, or failure to thrive. These signs may raise suspicion of celiac disease as it can interfere with nutrient absorption in children.
  • Autoimmune Diseases: When patients are diagnosed with autoimmune disorders such as type 1 diabetes, rheumatoid arthritis, or autoimmune thyroid disease, practitioners may use the Celiac Disease Test. These conditions are associated with an increased risk of celiac disease, and screening can be beneficial.
  • Family History: Individuals with a history of celiac disease have a higher risk of developing the condition. Therefore, practitioners might recommend the test for individuals with close relatives with a confirmed diagnosis.
  • Dermatological Symptoms: Dermatologists consider the Celiac Disease Test when patients exhibit skin conditions like dermatitis herpetiformis, characterized by itchy, blistering rashes. Dermatitis herpetiformis is strongly linked to celiac disease.
  • Suspected Gluten Sensitivity: For patients who report gluten sensitivity or non-specific gastrointestinal complaints in response to gluten consumption, the Celiac Disease Test can help determine if celiac disease is the underlying cause.
  • Monitoring Celiac Disease Management: After an initial diagnosis of celiac disease, healthcare providers may use the test to monitor the effectiveness of a gluten-free diet and check for any ongoing antibody production, ensuring the patient's condition is well-controlled.

What do the Results Mean?

Interpreting the results of a Celiac Disease Test is a critical step in diagnosing and managing this autoimmune condition. Here's what common test results mean:

  • Negative Results: A negative result on the Celiac Disease Test means that the antibodies associated with the disease were not detected in the blood, indicating that celiac disease is unlikely the cause of symptoms. False negatives are possible, especially if the individual has recently started a gluten-free diet or the disease is in its early stages.
  • Positive Results: A positive Celiac Disease Test indicates elevated celiac-related antibodies in the blood, a strong indicator of the condition. Further confirmation is sought through a small intestine biopsy, as positive results mean that gluten is causing damage to the intestine's lining.
  • Indeterminate Results: Sometimes, test results are inconclusive, which means that further testing or monitoring may be recommended to clarify the diagnosis.
  • Follow-Up Biopsy: A positive Celiac Disease Test result usually leads to a small intestine biopsy with a camera tube to confirm the diagnosis. Villous atrophy, or damage to the intestinal lining, confirms the diagnosis of celiac disease.
  • Management: Regardless of the test results, if celiac disease is confirmed, the primary treatment is a strict, lifelong gluten-free diet. This diet eliminates all sources of gluten, including wheat, barley, and rye, to prevent further damage to the small intestine and alleviate symptoms. Nutritional counseling may be recommended to help patients adapt to the dietary restrictions and ensure they receive essential nutrients.

Why use Carepatron as your Celiac Disease app?

Carepatron shines as the preferred platform for managing Celiac Disease testing and associated healthcare tasks, establishing itself as the top pick for those seeking a robust Celiac Disease Test app or Celiac Disease Test Software. Here's why Carepatron stands out:

  • Patient-Focused Approach: Carepatron places the patient experience at the forefront of its services. For individuals undergoing Celiac Disease testing, this translates into an intuitive interface that empowers them to keep track of appointments, access test results, and communicate effortlessly with their healthcare providers.
  • Seamless Health Records: Carepatron boasts advanced electronic health record (EHR) capabilities, simplifying the secure storage and retrieval of patient information. This feature proves vital in managing chronic conditions like Celiac Disease, where a long-term health data repository is indispensable.
  • Effortless Appointment Booking: Patients can conveniently schedule Celiac Disease tests and subsequent appointments within the platform. This streamlines the booking process and ensures individuals receive timely care.
  • Centralized Communication Hub: Effective communication between patients and healthcare providers is paramount in managing Celiac Disease. Carepatron is a centralized hub for secure messaging, allowing patients to seek guidance, share concerns, and stay engaged with their healthcare team.
  • Efficient Test Result Access: Through Carepatron, patients can swiftly access their Celiac Disease test results online, reducing the anxious wait time for crucial information. The software facilitates efficient result review and discussion between healthcare providers and patients.
  • Medication Adherence Support: For Celiac Disease patients who may also manage other health aspects, such as medication adherence, Carepatron offers reminders and notifications to ensure consistent and timely treatment.
  • Tailored Care Plans: Carepatron empowers healthcare providers to craft personalized care plans tailored to the unique requirements of Celiac Disease patients. These plans encompass dietary guidance, follow-up appointments, and access to educational resources.
Practice Management Software


  • Celiac disease - Diagnosis and treatment - Mayo Clinic. (2023, September 12). https://www.mayoclinic.org/diseases-conditions/celiac-disease/diagnosis-treatment/drc-20352225#:~:text=Two%20blood%20tests%20can%20help,to%20rule%20out%20celiac%20disease.
  • Celiac disease screening. (n.d.). https://medlineplus.gov/lab-tests/celiac-disease-screening/
  • Celiac disease screening | Celiac Disease Foundation. (n.d.). Celiac Disease Foundation. https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/
  • Celiac Disease testing and diagnosis | BeyondCeliac.org. (2023, May 30). Beyond Celiac. https://www.beyondceliac.org/celiac-disease/get-tested/
  • Celiac disease tests. (2022). National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/professionals/clinical-tools-patient-management/digestive-diseases/celiac-disease-health-care-professionals
  • How Do I Know If I Have Celiac Disease? (2017, January 4). WebMD. https://www.webmd.com/digestive-disorders/celiac-disease/celiac-disease-diagnosis-tests
  • Professional, C. C. M. (n.d.). Celiac disease. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/14240-celiac-disease
  • Website, N. (2023, April 4). Diagnosis. nhs.uk. https://www.nhs.uk/conditions/coeliac-disease/diagnosis/
Who typically requests a Celiac Disease Test?
Who typically requests a Celiac Disease Test?

Commonly asked questions

Who typically requests a Celiac Disease Test?

Healthcare providers, including primary care physicians, gastroenterologists, pediatricians, and specialists in related fields, typically request a Celiac Disease Test based on patient symptoms, risk factors, or medical history.

When are Celiac Disease Tests used?

Celiac Disease Tests are used when individuals present symptoms like chronic diarrhea, abdominal pain, unexplained weight loss, or a suspicion of celiac disease due to factors like family history or autoimmune conditions.

How are Celiac Disease Tests used?

Celiac Disease Tests involve collecting blood samples to detect specific antibodies related to celiac disease. A small intestine biopsy may be performed for confirmation if initial tests are positive.

How long does a Celiac Disease Test take?

The blood sample collection for a Celiac Disease Test typically takes just a few minutes. The time for results varies but can range from a few days to a couple of weeks, depending on the laboratory and specific tests performed.

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