What is polymyalgia rheumatica?
Polymyalgia rheumatica (PMR) is a common condition marked by muscle stiffness and pain, primarily affecting individuals over 70, with a higher prevalence in women. The term “poly” signified many, and “myalgia” referred to muscle pain, with onset typically occurring after age 50.
Characterized by muscle pain and morning stiffness, particularly in the shoulders, hips, and neck, PMR can significantly impact daily activities. Unlike rheumatoid arthritis, PMR does not directly damage the joints. Instead, it is associated with systemic symptoms such as fatigue, fever, and weight loss.
PMR is closely linked to giant cell arteritis, another inflammatory condition that can cause headaches, jaw claudication, and vision problems. In some cases, a temporal artery biopsy is performed to diagnose giant cell arteritis. Distal tenosynovitis and carpal tunnel syndrome can also be present as features of PMR.
The diagnostic criteria of PMR are supported by the presence of elevated inflammatory markers, such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), along with clinical and laboratory manifestations. Previous corticosteroid treatment affect the presentation and diagnosis of the disease. In some cases, magnetic resonance imaging is used to detect characteristic inflammatory changes in PMR patients.
Management of polymyalgia rheumatica then often involves the use of corticosteroids as the initial treatment. The treatment of polymyalgia rheumatica aims to reduce inflammation and alleviate symptoms. Possible risk factors should also be addressed as a preventive measure.










