Bilirubin Blood

Discover the importance of the Bilirubin Blood Test in liver health. Learn about its uses, results, and interpretation for valuable insights.


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Written by
Joshua Napilay
Joshua Napilay
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Joshua Napilay

What is a Bilirubin Blood Test?

A , scientifically known as a serum bilirubin test, is a pivotal diagnostic tool in medical assessments. It serves the crucial purpose of quantifying the bilirubin concentration, a yellow pigment originating from the human body's decomposition of red blood cells. Bilirubin undergoes processing by the liver and eventually finds its way into bile, playing an integral role in waste elimination.

This test emerges as a cornerstone in evaluating liver functionality and identifying and continuously monitoring a spectrum of liver and blood-related disorders. Healthcare providers judiciously prescribe the Bilirubin Blood Test when there are suspicions of liver ailments, hemolytic anemia (a condition characterized by the accelerated destruction of red blood cells, surpassing their production rate), or the manifestation of specific telltale symptoms such as jaundice (a condition typified by the yellowing of the skin and the sclera of the eyes), darkened urine, or pale stools. These symptoms often act as red flags, signaling potential elevations in bilirubin levels warrant investigation.

The procedure entails the collection of a blood sample from the patient, which is subsequently dispatched to a specialized laboratory for comprehensive analysis. Within this analysis, the test distinguishes between two primary forms of bilirubin: indirect (unconjugated) bilirubin and direct (conjugated) bilirubin. The findings are instrumental in clinical diagnosis, where increased natural bilirubin levels may indicate liver or gallbladder dysfunction. In contrast, elevated indirect bilirubin levels may suggest underlying issues in the breakdown of red blood cells.

Printable Bilirubin Blood

Download this Bilirubin Blood, a pivotal diagnostic tool in medical assessment.

How does it work?

The Bilirubin Blood Test is a vital diagnostic tool that helps healthcare professionals assess liver function and detect various medical conditions. Here's a breakdown of how this test works:

Patient Preparation

Before the test, patients are usually advised to fast for a specific period (typically 4 to 12 hours) to ensure accurate results. Inform the healthcare provider about any medications, supplements, or herbal remedies you are taking, as some can affect bilirubin levels.

Blood Sample Collection

A trained phlebotomist or nurse will collect a blood sample, usually from a vein in the arm. The area is cleaned with an antiseptic, and a needle is inserted to draw the blood into a special collection tube.

Transport to Laboratory

The collected blood sample is carefully labeled with patient information and the date and time of collection. It is then transported to a clinical laboratory for analysis.

Laboratory Analysis

In the lab, the blood sample is centrifuged to separate the plasma (the liquid component of blood) from the cellular elements. The plasma is further processed to measure bilirubin levels.

Quantification of Bilirubin

Two primary forms of bilirubin are indirect (unconjugated) and direct (conjugated). A chemical reaction or spectrophotometry is used to quantify the concentration of these bilirubin types in the plasma.

Interpretation of Results

The laboratory reports the results to the healthcare provider, who interprets them based on reference ranges and the patient's clinical condition. Elevated bilirubin levels may suggest liver disease, hemolytic anemia, or other medical issues.

Patient Consultation

The healthcare provider discusses the results with the patient, explaining their significance and any necessary follow-up actions or treatments.

Bilirubin Blood Test Example (sample)

The Bilirubin Blood Test Requisition Form is an essential medical document crucial in diagnosing various conditions related to bilirubin levels and assessing liver function. It is used to request and document test results, which is critical in medicine. This form contains patient information, healthcare provider details, test specifications, and space for recording test results. 

Patients can easily access the Bilirubin Blood Test PDF sample and download it. This makes it convenient to bring to healthcare appointments for streamlined testing and accurate documentation. The form is user-friendly and provides a clear layout for recording test results. Healthcare providers find this a valuable form for efficiently managing their patient's medical history. 

The Bilirubin Blood Test Requisition Form is an essential tool in the medical field. It allows for efficient communication between healthcare providers and patients, accurately diagnosing and treating various conditions related to bilirubin levels.

Download this Bilirubin Blood Example:

Bilirubin Blood Test Example (sample)

When would you use this test?

The Bilirubin Blood Test is employed in various clinical scenarios, serving as a critical diagnostic tool to determine specific health conditions. Here's when healthcare practitioners would typically use this test:

  • Jaundice Evaluation: Physicians often order a Bilirubin Blood Test to identify the underlying cause when a patient presents with skin and eyes yellowing. Elevated bilirubin levels can indicate liver dysfunction or excessive red blood cell breakdown, aiding diagnosis.
  • Liver Function Assessment: Routine liver function assessments are conducted during annual check-ups or when patients exhibit symptoms like unexplained fatigue, abdominal pain, or nausea. The test helps gauge the overall health of the liver and identify liver diseases such as hepatitis, cirrhosis, or fatty liver disease.
  • Preoperative Assessment: Surgeons may request this test before liver or gallbladder surgery to evaluate the patient's liver function and assess the risk of postoperative complications.
  • Hemolytic Anemia Diagnosis: Hematologists use the Bilirubin Blood Test to diagnose and monitor hemolytic anemias, conditions characterized by increased destruction of red blood cells, leading to elevated bilirubin levels.
  • Neonatal Jaundice Screening: Pediatricians routinely employ this test in newborns to screen for neonatal jaundice, a common condition caused by the immature liver's inability to process bilirubin effectively.
  • Monitoring Chronic Liver Diseases: Hepatologists and gastroenterologists use the test to monitor the progression of chronic liver conditions such as liver cirrhosis, autoimmune hepatitis, or non-alcoholic fatty liver disease over time.
  • Cancer Assessment: Oncologists may include Bilirubin Blood Tests in cancer screenings, as certain malignancies can impact liver function and cause bilirubin elevation.

Healthcare practitioners utilize the Bilirubin Blood Test based on specific clinical indications and patient symptoms. It plays a pivotal role in diagnosing liver disorders, anemia, and neonatal jaundice and monitoring various medical conditions, ensuring timely and appropriate medical interventions when needed.

What do the results mean?

A Bilirubin Blood Test results provide valuable insights into a patient's liver function and overall health. The test measures two main types of bilirubin: indirect (unconjugated) bilirubin and direct (conjugated) bilirubin. Understanding these results is crucial for healthcare professionals in diagnosing and managing various medical conditions. Here's what expected Bilirubin Blood Test results mean:

Normal Range

Normal total bilirubin levels typically fall within the range of 0.2 to 1.2 milligrams per deciliter (mg/dL) of blood. Within this range, bilirubin levels are considered healthy, indicating that the liver effectively processes bilirubin.

Elevated Total Bilirubin

Elevated total bilirubin levels (hyperbilirubinemia) can indicate several conditions, such as liver diseases (like hepatitis or cirrhosis) or hemolytic anemias (where red blood cells are destroyed faster than they are produced). The test distinguishes direct and indirect bilirubin to provide further insights into the underlying cause.

Elevated Indirect Bilirubin

Elevated indirect bilirubin levels often suggest that excessive breakdown of red blood cells (hemolysis) is occurring. This can be due to conditions like hemolytic anemia or Gilbert syndrome, a benign genetic condition.

Elevated Direct Bilirubin

Elevated direct bilirubin levels typically point to issues with the liver's ability to process bilirubin or obstructed bile flow. This can be seen in conditions like cholestasis or biliary obstruction.

Neonatal Jaundice

In newborns, elevated bilirubin levels are expected and often referred to as neonatal jaundice. Mild jaundice usually resolves independently, but severe cases may require treatment to prevent complications.

Interpreting Bilirubin Blood Test results requires considering a patient's medical history, symptoms, and other tests. Abnormal results may prompt further investigation and interventions. A free trial allows for early identification of liver issues.

Why use Carepatron as your Bilirubin Blood app?

Choosing Carepatron as your Bilirubin Blood Test app and software provider offers several compelling reasons that make it the ideal platform for this type of work.

  • Comprehensive Clinical Support: Carepatron is renowned for offering a holistic suite of clinical support tools. Its Bilirubin Blood Test app is just one facet of its comprehensive healthcare ecosystem. It ensures that healthcare practitioners can access all the necessary tools for accurate diagnostics and patient care.
  • User-Friendly Interface: Carepatron's Bilirubin Blood Test software boasts an intuitive and user-friendly interface. This simplicity is crucial for healthcare professionals, allowing them to focus on patient care rather than navigating complex software.
  • Streamlined Workflow: The software streamlines the entire process of ordering, conducting, and interpreting Bilirubin Blood Tests. It simplifies requisition forms, automates result analysis, and provides transparent, easy-to-understand reports, saving time and reducing the risk of errors.
  • Integration Capabilities: Carepatron understands the importance of seamless integration with existing healthcare systems. Its Bilirubin Blood Test app and software can be integrated with electronic health records (EHRs) and other clinical platforms, ensuring a cohesive patient care experience.
  • Data Security and Compliance: Carepatron places the utmost importance on data security and compliance with healthcare regulations. The Bilirubin Blood Test app follows strict privacy and security protocols, ensuring patient data is always protected.
  • Regular Updates and Support: The company is committed to continuous improvement. Carepatron regularly updates its Bilirubin Blood Test software, incorporating the latest advancements in medical technology and responding to user feedback. Their customer support is also readily available to assist with queries or issues.
  • Evidence-Based Practice: Carepatron's Bilirubin Blood Test software is built on evidence-based practices and adheres to industry standards. This ensures that healthcare practitioners can rely on accurate and clinically validated results.
Clinical Documentation Software


Bilirubin blood test. (n.d.-a).

Bilirubin blood test. (n.d.-b). Mount Sinai Health System.

Bilirubin Test | HealthLink BC. (n.d.).

Bilirubin test - Mayo Clinic. (2022, October 8).

Lu, C. M., MD PhD. (2022, November 29). Bilirubin test -

MacGill, M. (2023, January 4). What causes high bilirubin levels?

Professional, C. C. M. (n.d.). Bilirubin test. Cleveland Clinic.

Rossiaky, D. (2023, September 11). What causes high bilirubin? Healthline.

Total Bilirubin (Blood) - Health Encyclopedia - University of Rochester Medical Center. (n.d.).

What is a bilirubin test? (2017, February 28). WebMD.

Who typically requests a Bilirubin Blood Test?
Who typically requests a Bilirubin Blood Test?

Commonly asked questions

Who typically requests a Bilirubin Blood Test?

Healthcare providers, including primary care physicians, specialists (e.g., gastroenterologists, hematologists), surgeons, and pediatricians, typically request Bilirubin Blood Tests.

How are Bilirubin Blood Tests used?

A blood sample is drawn from the patient and sent to a lab for analysis. The test measures bilirubin levels, distinguishing between indirect and direct bilirubin.

How long does a Bilirubin Blood Test take?

The test itself typically takes just a few minutes to draw blood. Results are usually available within a day or two, depending on the lab's processing time.

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