What is cuboid syndrome?
The cuboid bone is one of the seven small tarsal bones in the foot, located on the lateral front side of the foot (near the little toe). Cuboid syndrome occurs when the cuboid bone moves out of proper alignment, causing stress on the surrounding tissues and ligaments. Also known as subluxation of the midtarsal joint, cuboid syndrome happens when the cuboid bone misaligns with the adjacent calcaneus bone.
Cuboid syndrome in the lateral midfoot leads to pain and dysfunction due to the subluxation or displacement of the cuboid bone. Risk factors for this condition include:
- Ankle sprains, especially inversion injuries
- Overuse from repetitive activities like running or dancing
- Excessive pronation or flat feet
- Poorly fitting shoes or orthotics
- Obesity
Common symptoms are lateral foot pain, difficulty walking, swelling, and reduced range of motion.










