F33.3 – Major depressive disorder, recurrent, severe with psychotic symptoms

Learn about the ICD-10-CM code F33.3 for major depressive disorder, recurrent, severe with psychotic symptoms. Explore clinical info, FAQs, and more.

By Karina Jimenea on May 21, 2025.

Fact Checked by Ericka Pingol.

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F33.3 – Major depressive disorder, recurrent, severe with psychotic symptoms

F33.3 diagnosis code: Major depressive disorder, recurrent, severe with psychotic symptoms

The F33.3 diagnosis code refers to major depressive disorder that is recurrent, meaning your client has had multiple episodes, not just a one-time experience. The "severe with psychotic symptoms" part means their depression is intense and includes features like delusions or hallucinations, which may not always be mood-congruent psychotic symptoms.

As a professional, you’ll want to closely monitor for safety risks and ensure coordinated care, as this level of severity often requires both medication and therapy.

Is F33.3 billable?

Yes, F33.3 is a billable code that can indicate a diagnosis of major depressive disorder, recurrent, severe, with psychotic symptoms for reimbursement purposes. The code is valid for submission on a claim form and accurately represents the patient's condition.

Clinical information

  • It affects individuals of all ages, although it is more common in adults.
  • The exact cause of major depressive disorder is unknown but involves a combination of genetic, biochemical, environmental, and psychological factors.
  • Stressful life events may trigger a depressive episode, increasing the risk of developing recurrent episodes.
  • Treatment involves a combination of psychotherapy, antidepressant medications, and antipsychotic medications to manage symptoms and prevent relapses.
  • Early intervention and ongoing symptom monitoring are crucial for improving the patient’s quality of life, especially when the condition co-occurs with other behavioral disorders.

Synonyms include

  • Recurrent severe depression with psychosis
  • Recurrent severe episodes of psychotic depression
  • Severe recurrent depressive disorder with psychotic features
  • Recurrent major depression with psychotic symptoms
  • Severe depressive episode with psychotic features, recurrent
  • Psychotic major depressive disorder, recurrent

Other ICD-10 codes commonly used for major depressive disorder

Frequently asked questions

What are the symptoms of major depressive disorder, recurrent, severe with psychotic symptoms?

Symptoms include recurrent episodes of severe depression accompanied by hallucinations, delusions, or severe thought disturbances, leading to significant impairment in daily functioning.

How is major depressive disorder, recurrent, severe with psychotic symptoms diagnosed?

A mental health professional will conduct a thorough assessment, including a detailed history and clinical evaluation, to rule out other conditions and determine the most appropriate treatment plan.

What is the difference between F33.3 and F31.5?

Both major depression and bipolar disorder are mood disorders but F33.3 is major depressive disorder, recurrent and severe, with psychotic symptoms, meaning the client has had multiple depressive episodes without any history of mania. On the other hand, F31.5 is bipolar disorder, current episode depressed, severe, with psychotic features but the client has a history of manic or hypomanic episodes.

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