F05: Delirium due to known physiological condition

F05: Delirium due to known physiological condition

Learn F05 - Delirium due to known physiological conditions, clinical insights, billability, and related codes.

By Audrey Liz Perez on Jul 16, 2025.

Fact Checked by Karina Jimenea.

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F05 diagnosis code: delirium due to known physiological condition

Delirium (F05) is a serious disturbance in mental abilities that results in confused thinking and reduced awareness of the environment. This International Classification of Diseases code is used when delirium arises due to a known physiological condition, such as infections, metabolic disorders, head trauma, or withdrawal from certain substances.

F05 is part of a broader category that includes mental disorders due to known physiological conditions, distinguishing it from primary psychiatric conditions or other specified mental disorders.

It reflects how a systemic disease affecting the body, notably the brain or central nervous system, can lead to profound mental changes. These disturbances are classified under mental and behavioral disorders in the ICD-10-CM but must be linked to diseases classified elsewhere (like infections or organ failure). Properly identifying this relationship is essential for accurate diagnosis and treatment.

It's characterized by acute or subacute onset, fluctuating levels of consciousness, disorientation, hallucinations, and disturbances in cognitive functions such as attention, memory, and perception.

Is F05 billable?

Yes, F05 is a billable and specific ICD-10-CM diagnosis code that can be used for reimbursement purposes. Accurate diagnosis and additional code may be essential for identifying etiology and treatment, and for avoiding claim denials.

Clinical information

Delirium due to a known physiological condition may occur in patients with:

  • Infections, such as UTIs or pneumonia
  • Metabolic imbalances, such as low sodium or liver/kidney failure
  • Head trauma, stroke, or brain tumors
  • Withdrawal from medications or psychoactive substances
  • Postoperative complications or prolonged hospitalization for other conditions

Delirium is a syndrome encompassing disturbances in attention, awareness, and cognition. It develops over a short period and tends to fluctuate during the day. As it's often reversible, timely recognition and treatment of the underlying condition are crucial.

In addition to treating the underlying cause, managing the symptoms of delirium is also essential. This often includes measures to ensure patient safety, manage agitation, and provide a supportive environment.

Synonyms include

  • F05 Delirium
  • Acute confusional state
  • Acute organic brain syndrome
  • Delirium due to systemic disease
  • Delirium superimposed on dementia
  • Delirium of mixed origin
  • Hypoactive delirium
  • Psycho-organic syndrome
  • Delirium with hallucinations or delusions
  • Delirium due to alcohol and other psychoactive substances
  • Alcohol induced or unspecified delirium
  • Unspecified dementia with delirium

Related ICDs

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