F11.23 – Opioid dependence with withdrawal

Read about F11.23, opioid dependence with withdrawal. Learn its clinical meaning, billability, related ICD-10-CM codes, synonyms, and more.

By Karina Jimenea on Aug 8, 2025.

Fact Checked by Gale Alagos.

Use Code

F11.23 diagnosis code: Opioid dependence with withdrawal

F11.23 refers to opioid dependence with withdrawal. It falls under the F11 category for opioid-related disorders, which is included in the broader F10–F19 range for mental and behavioral disorders resulting from psychoactive substance use.

This code refers to a state where an individual has developed a dependence on opioids. Dependence implies that the person needs to use the drug to avoid experiencing withdrawal symptoms continually. Withdrawal symptoms are physical and mental symptoms that occur after stopping or reducing drug intake.

F11.23 billable?

Yes, F11.23 is a billable code, indicating that it can be used for medical billing and reimbursement.

Clinical information

Opioids are a group of drugs that include legal (prescription pain relievers) and illegal substances (heroin) which can lead to opioid addiction.
Opioid dependence is a chronic medical condition induced by repeated use of opioids leading to significant impairment or distress.
Withdrawal symptoms typically include, but are not limited to, restlessness, insomnia, diarrhea, vomiting, and involuntary leg movements.
Treatment often involves medications, counseling, and support from family and friends.

Synonyms include

Delirium due to opioid withdrawal
Opioid withdrawal delirium

Other ICD-10 codes commonly used for opioid use

F11.159: Opioid abuse with opioid-induced psychotic disorder, unspecified
F11.20: Opioid dependence, uncomplicated
F11.21: Opioid dependence, in remission
F11.220: Opioid dependence with intoxication, uncomplicated
F11.221: Opioid dependence with intoxication delirium
F11.222: Opioid dependence with intoxication with perceptual disturbance
F11.229: Opioid dependence with intoxication, unspecified
F11.24: Opioid dependence with opioid-induced mood disorder
F11.251: Opioid dependence with opioid-induced psychotic disorder with hallucinations
F11.259: Opioid dependence with opioid-induced psychotic disorder, unspecified
F11.29: Opioid dependence with unspecified opioid-induced disorder
F11.920: Opioid use, unspecified with intoxication, uncomplicated
F11.981: Opioid use, unspecified with opioid-induced sexual dysfunction
F11.982: Opioid use, unspecified with opioid-induced sleep disorder
F11.988: Opioid use, unspecified with other opioid-induced disorder

Commonly asked questions

OUD stands for opioid use disorder, which is a medical condition characterized by the problematic use of opioid drugs, leading to significant impairment or distress. It includes a pattern of compulsive opioid use despite harmful consequences.

The ultimate goal of treatment for opioid dependence is to help individuals achieve and maintain long-term recovery by reducing or eliminating opioid use.

Diagnosis code F11.23 refers to opioid dependence with withdrawal. It is part of the F11 category for opioid-related disorders, which fall under mental and behavioural disorders due to psychoactive substance use.

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