F32.3 – Major depressive disorder, single episode, severe with psychotic features

Learn more about the diagnosis code F32.3: Major depressive disorder, single episode, severe with psychotic features, its associated symptoms, and more.

By Patricia Buenaventura on Apr 27, 2025.

Fact Checked by Karina Jimenea.

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F32.3 – Major depressive disorder, single episode, severe with psychotic features

F32.3 diagnosis code: Major depressive disorder, single episode, severe with psychotic features

F32.3 is a diagnosis code under the International Classification of Diseases, 10th Revision Clinical Modification (ICD-10-CM). It identifies as major depressive disorder, single episode, severe with psychotic features. This code, under the mood disorders block, applies to a person who has had at least one episode of major depression marked by depressed mood and having some symptoms of psychosis. 

While F32.3 is similar to F32.2 (major depressive disorder, single episode, moderate), F32.3 clearly indicates psychotic features present during the episode of depression.

Psychotic symptoms associated with this diagnosis may include delusions or hallucinations. Other common symptoms of major depression with psychotic features include confusion or disorganization, social withdrawal, and changes in appetite or sleeping habits.

Is F32.3 billable? 

Yes, this ICD-10 code is billable.

Clinical information

The criteria for F32.3 Major depressive disorder, single episode, severe with psychotic features, include a period of at least two weeks in which the majority of days are characterized by a depressed mood and markedly diminished interest or pleasure in almost all activities and at least four additional symptoms from the list below must also be present:

  • Significant weight loss
  • Insomnia or hypersomnia
  • Psychomotor agitation or retardation
  • Fatigue/loss of energy
  • Feelings of worthlessness, excessive guilt
  • Difficulty concentrating or making decisions
  • Recurrent thoughts of death and suicidal ideation

Treatment for psychotic depression, which is a subtype of major depressive disorder and psychotic disorder, vary depending on the severity of one's symptoms. It often includes a combination of medication and psychotherapy, such as cognitive behavioral therapy (CBT). Medication may include antidepressants to balance brain chemicals or help stabilize moods.

Synonyms include

  • Psychotic depression, single episode
  • Major depressive disorder with psychotic symptoms, single episode
  • Depression major single severe with psychotic features
  • Severe major depression, single episode, with psychotic features
  • Single major depressive episode, severe, with psychosis

Other ICD-10 codes commonly used for major depressive disorder

These are several other codes commonly used for a major depressive disorder diagnosis:

Frequently asked questions

What is diagnosis code F32.3?

F32.3 identifies as major depressive disorder, single episode, severe with psychotic features.

Is F32.3 billable?

Yes, it is a billable code.

What are the common treatments for F32.3?

Treatment may vary depending on the severity of one's symptoms. It often includes a combination of medication and psychotherapy, such as cognitive behavioral therapy (CBT).

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