F33.1 – Major Depressive Disorder, Recurrent, Moderate

F33.1 – Major Depressive Disorder, Recurrent, Moderate

Learn more about the F33.1 ICD-10 code for major depressive disorder, recurrent, moderate, its clinical information, and synonyms.

By Gale Alagos on Jul 16, 2025.

Fact Checked by Karina Jimenea.

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F33.1 diagnosis code: Major depressive disorder, recurrent, moderate

F33.1 is the ICD-10 code for major depressive disorder, recurrent, moderate, a mental health condition characterized by repeated episodes of moderate depression. This ICD-10 code specifically identifies moderate major depressive disorder with recurrent episodes, distinguishing it from a single episode presentation.

Patients with this recurrent depressive disorder experience persistent sadness, hopelessness, and loss of interest in activities they once enjoyed during each current episode. Symptoms may include changes in appetite and sleep patterns, fatigue, difficulty concentrating, feelings of worthlessness or guilt, and thoughts of death or suicide, but without psychotic features.

Episodes typically last at least two weeks and may significantly impact daily functioning, relationships, and overall quality of life. This condition differs from bipolar disorder as it does not include manic episodes or mixed affective episodes.

Early diagnosis and treatment are crucial to help patients manage their condition and reduce the risk of recurrence.

Is F33.1 billable?

F33.1 is a billable ICD-10 code, meaning healthcare professionals can use it for insurance claims and reimbursement purposes. Accurate coding is essential for proper documentation and treatment planning for patients diagnosed with major depressive disorder, recurrent, moderate.

Clinical information

  • Treatment for moderate major depressive disorder with recurrent episodes often involves a combination of medication and psychotherapy.
  • This affective disorder requires careful monitoring to distinguish it from bipolar disorder, particularly when assessing for any history of manic episodes.
  • Antidepressent medications, such as selective serotonin reuptake inhibitors (SSRIs), can help alleviate symptoms and prevent future depressive episodes.
  • Psychotherapy approaches like cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT) can help patients develop coping strategies and manage anxiety that often co-occurs with depression.
  • Clinicians must assess for psychotic features to differentiate from severe psychotic presentations and rule out psychotic symptoms.
  • Chronic depression patterns require evaluation for seasonal pattern variations or mixed features that might indicate moderate depression with seasonal pattern or moderate depression with mixed features specifiers.
  • Regular follow-up appointments with healthcare providers are vital for monitoring progress and adjusting treatment plans, especially given the recurrent nature.
  • In addition to professional treatment, lifestyle changes and support from loved ones can play a crucial role in managing this mental health condition.

Synonyms include

  • Recurrent moderate depression
  • Moderate depressive disorder, recurrent
  • Moderate recurrent major depression
  • Moderate major depressive disorder, recurrent
  • Moderate depression, recurrent
  • Depression, major, recurrent, moderate
  • Major depression, recurrent, moderate
  • Major depression recurrent episodes, moderate
  • Recurrent episodes of depressive reaction
  • Recurrent episodes of endogenous depression
  • Recurrent episodes of reactive depression
  • Recurrent episodes of major depression
  • Recurrent moderate major depressive disorder co-occurrent with catatonia
  • Major depressive disorder, recurrent episode, moderate w peripartum onset
  • Major depressive disorder, recurrent episode, moderate w seasonal pattern

Other ICD-10 codes commonly used for major depressive disorder

Related ICDs

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