Neutropenic Fever ICD-10-CM Codes

Read this short guide and learn about neutropenic fever ICD codes you can use. Discover billing and clinical information.

By Patricia Buenaventura on Aug 8, 2025.

Fact Checked by RJ Gumban.

Use Code

What neutropenic fever ICD codes can I use?

There are no specific neutropenic fever ICD codes for billing and coding. However, you can use the following ICD codes instead:

D70.9 - Neutropenia, unspecified

This ICD-10 code is meant to be used on a patient confirmed to have neutropenia. As to what caused it, well, it’s unspecified. Since it’s possible to get a fever caused by neutropenia, referred to as neutropenic fever or febrile neutropenia,, this ICD-10 code can be used.

D70.8 - Other neutropenia

This is the same as Item 1. But it’s best used only if your patient has neutropenia that doesn’t have a specific ICD-10 code.

P61.5 - Transient neonatal neutropenia

This ICD-10 code is meant for neonatal patients confirmed to have transient neonatal neutropenia. If they have a fever accompanying the neutropenia, you may use this ICD-10 code.

R50.81 - Fever presenting with conditions classified elsewhere

This ICD-10 code is meant to be used on patients confirmed to have fever as a result of certain conditions. You may use this for neutropenic fever cases.

Are these neutropenic fever ICD codes billable?

Yes. The aforementioned neutropenic fever-related ICD-10 codes are valid and billable.

Clinical information

Neutropenic fever is a serious condition most commonly observed in patients undergoing cancer treatments, particularly chemotherapy. It arises due to a low count of neutrophils, a white blood cell that fights infections.
Symptoms include a high fever exceeding 100.4°F (38°C), alongside other signs like chills, sweating, sore throat, abdominal pain, and breath shortness.
Patients with neutropenic fever are highly susceptible to infections, as their immune system lacks the necessary defense. Even minor injuries or infections can escalate rapidly.
Immediate medical attention is crucial to combat the potential life-threatening infections associated with this condition. Treatment often involves hospitalization, antibiotics, and antifungal medicines.
Preventative measures include practicing good hygiene, avoiding crowded places, and adhering to a diet that minimizes the risk of food-borne infections.

Synonyms include:

Adult chronic idiopathic neutropenia
Chronic idiopathic neutropenia
Immune neutropenia
Neutropenia associated with infectious disease
Neutropenia with AIDS
Neutropenic disorder
Refractory neutropenia
Acquired neutropenia
Febrile neutropenia

Commonly asked questions

Yes, but we don’t recommend using them because they are invalid.

Healthcare professionals will conduct a complete blood count. They might take a sample of bone marrow if needed.

Healthcare professionals may administer/prescribe antibiotics, corticosteroids, and/or G-CSFs.

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