What ICD-10 Codes are Used for Sickle Cell Disease
These Sickle Cell Disease ICD Codes classify different aspects, including anemia, traits, specific genetic combinations, and variations.
D57
Sickle-cell disorders, primarily sickle cell anemia (or sickle cell disease), are genetic ailments arising from a mutation in the hemoglobin gene. This mutation gives rise to abnormal hemoglobin called hemoglobin S (HbS). Under deoxygenated conditions, HbS causes red blood cells to become inflexible and assume a characteristic sickle or crescent shape.
D57.1
Unlike sickle cell anemia, this trait generally doesn't cause severe complications, but slight risks like exertional rhabdomyolysis may be present. This code covers the sickle-cell trait, a genetic condition where an individual carries one normal hemoglobin gene (HbA) and one sickle hemoglobin gene (HbS).
D57.2
Characterized by the inheritance of two distinct abnormal hemoglobin genes, resulting in the combination of different gene variants. This unique genetic makeup can lead to various symptoms and clinical presentations.
D57.8
Encompasses a diverse group of sickle-cell disorders that extend beyond the common sickle-cell anemia. These disorders may involve combinations of abnormal hemoglobin genes, leading to distinct clinical characteristics.
D57.81
Occurs when an individual inherits sickle hemoglobin (HbS) and hemoglobin C (Hb-C) genes. This combination gives rise to a unique set of clinical manifestations, which may differ from other types of sickle cell disorders.
D57.89
Covers specific sickle cell disorders that have distinct features but do not fit precisely into other predefined categories. This code accounts for various less common variations and subtypes of sickle cell conditions.
