Neutropenia ICD-10-CM Codes

Discover commonly used ICD-10 codes for Neutropenia. Understand how these codes aid in diagnosing and treating this condition.

By Patricia Buenaventura on Aug 8, 2025.

Fact Checked by Karina Jimenea.

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What ICD-10 codes are used for neutropenia?

Neutropenia, a condition marked by abnormally low levels of neutrophils in the blood, is a significant medical concern. Accurate coding of neutropenia diagnoses is vital for medical billing, healthcare records, and effective patient care. Several commonly used codes in the ICD-10 coding system encompass various aspects of neutropenia.

Here, we highlight such neutropenia ICD-10 codes, along with clinical descriptions for each:

D70.0: Congenital agranulocytosis

This code is used when neutropenia is severe congenital, also known as infantile genetic agranulocytosis or Kostmann's disease.

D70.1: Agranulocytosis secondary to cancer chemotherapy

This code can be used for neutropenia caused by cancer treatments like chemotherapy.

D70.2: Other-drug induced agranulocytosis

For drug-induced neutropenia, this code is the most appropriate.

D70.3: Neutropenia due to infection

This code is best used for neutropenia that's caused by or associated with an infectious disease.

D70.4: Cyclic neutropenia

For periodic neutropenia or cyclic neutropenia, healthcare providers must use this code.

D70.8: Other neutropenia

Neutropenia can manifest in diverse ways, often related to specific underlying causes that don't fit into other predefined categories.

D70.9: Neutropenia, unspecified

When the specific type or cause of neutropenia is not identified, this general code is applied for broader categorization.

P61.5: Transient neonatal neutropenia

This code is for babies with isoimmune neutropenia or neonatal alloimmune neutropenia (NAN).

Neutropenia can result from various underlying factors, including medications, infections, autoimmune diseases, and bone marrow disorders. Accurate ICD-10 coding not only ensures the efficient management of patients but also facilitates correct billing procedures.

When using these codes, healthcare professionals should include detailed clinical descriptions to provide a comprehensive overview of the patient's condition, helping in precise diagnosis and appropriate treatment planning.

Which neutropenia ICD codes are billable?

All of the aforementioned and commonly used ICD-10 codes for neutropenia are billable. They are essential for accurately documenting and classifying neutropenia cases in medical billing and healthcare records, ensuring proper reimbursement and appropriate patient care. However, adhering to specific coding guidelines and supporting clinical documentation for accurate billing and claim processing is essential.

Clinical information

Neutropenia is a medical condition characterized by a decreased number of neutrophils, a type of white blood cell essential for immune system function.
Neutropenia can range from mild to severe, with the severity often determined by the absolute neutrophil count (ANC). Severe neutropenia is more vulnerable to infections.
Neutropenia can result from various causes, including congenital factors, medications (e.g., chemotherapy), autoimmune diseases, infections, and bone marrow disorders.
Neutropenia increases the risk of infections, especially those caused by bacteria. It may lead to recurrent or severe bacterial infections.
Patients with neutropenia may exhibit symptoms such as fever, mouth sores, skin infections, and other signs of a compromised immune system.
Specific ICD-10 codes are used to document and classify neutropenia diagnoses for billing and medical records, helping healthcare providers to identify the underlying cause and plan appropriate treatment.
Treatment for neutropenia depends on the cause and severity but often includes addressing the underlying issue, administering growth factors to stimulate neutrophil production, and prophylactic antibiotics to prevent infections.
The prognosis for neutropenia varies based on its cause and severity. With proper management and treatment, many individuals with neutropenia can lead healthy lives.
Reducing the risk of infections is crucial for individuals with neutropenia. This includes practicing good hygiene, avoiding sick individuals, and following healthcare provider guidance.
Regular monitoring of neutrophil counts through blood tests like a complete blood count is necessary to assess treatment effectiveness and the patient's risk of infection.
To provide comprehensive care, neutropenia often requires a collaborative approach involving hematologists, infectious disease specialists, and other healthcare professionals.

Synonyms include

Agranulocytosis, chronic
Agranulocytosis, pernicious
Absolute neutrophil count (ANC) Deficiency
Neutrophil deficiency
Decreased neutrophils
Low neutrophil count
Chronic idiopathic neutropenia
Febrile neutropenia

Commonly asked questions

ICD codes for neutropenia should be used when a patient has a confirmed diagnosis of neutropenia or as a secondary code to indicate its presence when associated with other conditions.

Yes, neutropenia diagnosis codes are billable when appropriately documented. They are essential for medical billing and insurance reimbursement.

Treatment for neutropenia varies but may include addressing underlying causes, administering growth factors to stimulate neutrophil production, and prescribing prophylactic antibiotics to prevent infections.

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