Lymphadenopathy ICD-10-CM Codes

Explore this short guide to ICD-10 codes for lymphadenopathy. Learn more about the codes’ billability, synonyms, and clinical descriptions. 

By Olivia Sayson on Feb 29, 2024.

Fact Checked by Nate Lacson.

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Lymphadenopathy ICD-10-CM Codes

What ICD-10 Codes are Used for Lymphadenopathy 

Here’s a list of the ICD-10 CM codes used for Lymphadenopathy:

  • R59: Enlarged lymph nodes
  • R59.0: Localized enlarged lymph nodes 
  • R59.1: Generalized enlarged lymph nodes
  • R59.9: Enlarged lymph nodes, unspecified. 

Do note that according to ICD-10-CM guidelines, you may only use this code when you or the referring physician has made a definitive, principal diagnosis. 

Which Lymphadenopathy ICD codes are Billable: 

  • No, the R59: Enlarged lymph node code is not billable because it’s not specific enough. 
  • Yes, the R59.0: Localized enlarged lymph node code is billable.
  • Yes, the R59.1: Generalized enlarged lymph node code is billable. 
  • Yes, the R59.9: Enlarged lymph nodes, unspecified code is billable. 

Clinical Information

  • Lymphadenopathy is when a person’s lymph nodes swell as a natural reaction to infection or illness. Swollen lymph nodes signify that the immune system is working to fight the disease.
  • Although, it’s more common for people to think that swollen lymph nodes are only located on the neck. However, it can also be found and get swollen around the jaw, chest, arms, abdomen, and leg area. 
  • A patient has lymphadenopathy if their lymph nodes are more significant in size, feel painful/tender when touched, are hard or rubbery in consistency, and if they feel like they’re connected. It’s also possible that these symptoms may be combined with the illness or infection that the patient has. 
  • Causes of lymphadenopathy may vary depending on the location of the swollen nodes. Some common causes are upper respiratory infections, other conditions caused by bacteria/viruses, and STIs. 
  • Usually, swollen lymph nodes get better without treatment. However, if treatment is recommended, it depends on the lymph node's cause. The most common treatment is medication. However, if the lymph nodes are because of cancer, treatment may involve chemotherapy. 

Synonyms Include:

  • Deep lymphadenopathy
  • Persistent generalized lymphadenopathy
  • Reactive lymphadenopathy
  • Superficial lymphadenopathy
  • Swelling or tenderness of lymphoreticular structure
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Commonly asked questions

When to use a Lymphadenopathy ICD code?

You can use a lymphadenopathy ICD code when determining that the patient has swollen lymph nodes and when you’ve made a definitive, principal diagnosis beforehand.

Are Lymphadenopathy diagnosis codes billable?

Yes, lymphadenopathy ICD-10 CM codes are billable. 

What are the common treatments for Lymphadenopathy Diagnosis?

The most common treatment for lymphadenopathy is medication. 

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