Hepatosplenomegaly ICD-10-CM Codes

Hepatosplenomegaly ICD-10-CM Codes

Discover the 2023 ICD-10-CM codes for Hepatosplenomegaly. This guide elaborates on billable codes, clinical info, and more about Hepatosplenomegaly.

By Emma Hainsworth on Aug 8, 2025.

Fact Checked by Ericka Pingol.

Use Code

What ICD-10 codes are used for hepatosplenomegaly?

Being aware of the Hepatosplenomegaly ICD-10 codes is crucial for a precise diagnosis. There is one standard code used:

  • R16.2 - Hepatomegaly with splenomegaly, not elsewhere classified: This code is typically used when the patient's medical records indicate the concurrent presence of an enlarged liver and spleen, and the condition isn't classified elsewhere.

Which hepatosplenomegaly ICD-10 codes are billable?

Understanding billable hepatosplenomegaly ICD codes is fundamental for smooth medical billing:

  • R16.2: Yes, billable. This code applies to cases where patients simultaneously present with both hepatomegaly (enlarged liver) and splenomegaly (enlarged spleen).

Clinical information

Hepatosplenomegaly refers to an abnormal simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly):

  • Hepatosplenomegaly refers to an abnormal simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly):
  • It is not a disease but a sign of an underlying condition such as infection, metabolic disorder, hematological disease, or malignancy.
  • Common symptoms can include pain or fullness in the left upper abdomen that can spread to the left shoulder, feeling full without eating, or anemia. For example, these symptoms may appear in patients with cirrhosis or certain blood cancers.
  • Hepatosplenomegaly can be diagnosed through a physical examination and imaging studies like ultrasound or CT scan.
  • Treatment depends on the underlying cause. Addressing the cause can reduce the size of both the liver and spleen.

Synonyms include

  • Enlarged liver and spleen
  • Liver and spleen enlargement
  • Hepatosplenic enlargement
  • Hepatosplenomegaly NOS (not otherwise specified)

Other related codes

  • R16.0: Hepatomegaly, not elsewhere classified (enlarged liver alone)
  • R16.1: Splenomegaly, not elsewhere classified (enlarged spleen alone)

Commonly asked questions

Hepatosplenomegaly is an abnormal simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).

Hepatosplenomegaly is not a disease but a sign of an underlying condition such as infection, metabolic disorder, hematological disease, or malignancy.

Treatment for Hepatosplenomegaly depends on the underlying cause. Addressing the cause can reduce the size of the liver and spleen.

Related ICDs

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