Coronary Arteriosclerosis ICD-10-CM Codes

Coronary Arteriosclerosis ICD-10-CM Codes

Explore 2025 ICD-10-CM codes for coronary arteriosclerosis, including native artery, bypass graft, and angina types, plus diagnosis and treatment info.

By Wynona Jugueta on Aug 8, 2025.

Fact Checked by Gale Alagos.

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What are Coronary Arteriosclerosis ICD-10-CM Codes?

Coronary arteriosclerosis, also known as atherosclerotic heart disease, is a chronic condition where plaque (atheroma) builds up in the coronary arteries, reducing oxygen-rich blood flow to the heart muscle. This condition is captured in ICD-10-CM under the category I25, which covers a wide range of coronary artery disease codes related to chronic ischemic heart disease.

These codes help healthcare providers document and bill accurately for diseases of native coronary arteries, coronary artery bypass grafts, and involvement of transplanted hearts, as well as whether or not angina pectoris is present. They also reflect specific lesion types such as lipid-rich plaque and calcified coronary lesions.

Native coronary artery

  • I25.10 – Atherosclerotic heart disease of native coronary artery without angina pectoris
  • I25.110 – …with unstable angina pectoris
  • I25.111 – …with angina pectoris with documented spasm
  • I25.112 – …with refractory angina pectoris (introduced October 2022)
  • I25.118 – …with other forms of angina pectoris
  • I25.119 – …with unspecified angina pectoris

Coronary artery bypass graft(s) (CABG)

  • I25.810 – Atherosclerosis of coronary artery bypass graft without angina
  • I25.811 – …with angina pectoris
  • I25.812 – Atherosclerosis of bypass graft of coronary artery of transplanted heart without angina
  • I25.813 – …with angina pectoris
  • I25.814 – …with refractory angina pectoris

Transplanted heart (native or graft)

  • I25.820 – Atherosclerosis of native coronary artery of transplanted heart without angina
  • I25.821 – …with angina pectoris
  • I25.822 – …with refractory angina pectoris

Other specific conditions

  • I25.83 – Coronary atherosclerosis due to lipid-rich plaque
  • I25.84 – Coronary atherosclerosis due to calcified coronary lesion

Each code represents specific combinations of vessel type, angina type, and lesion composition—critical details for ICD-10 billing, risk stratification, and clinical decision-making.

Which Coronary Arteriosclerosis ICD-10-CM Codes are billable: 

All of the coronary arteriosclerosis ICD-10 codes listed above are billable under the 2025 ICD-10-CM updates. Providers should assign the most specific code that describes the patient’s condition, whether it involves the native coronary artery without angina, a bypass graft, or a transplanted heart.

In cases involving environmental or occupational risk exposures (e.g., environmental tobacco smoke, occupational exposure), an additional code may be used to indicate the contributing factor.

Clinical information

Coronary arteriosclerosis refers to atherosclerosis of the coronary vessels, characterized by the buildup of lipids, calcium, and fibrous tissue. It is a leading cause of myocardial infarction and is closely associated with non-ischemic myocardial injury in some cases.

Over time, this condition may result in chronic total occlusion, especially in patients with poorly controlled risk factors.

Symptoms usually don’t appear until the condition progresses. They may worsen during emotional or physical stress and include:

  • Chest pain or discomfort (angina pectoris)
  • Shortness of breath
  • Fatigue
  • Rapid or irregular heartbeat
  • Dizziness or fainting
  • Muscle weakness during exertion
  • Nausea

People at risk for atherosclerosis of the coronary artery include:

  • Older age
  • Family history of coronary artery disease
  • Environmental tobacco smoke or smoking
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Occupational exposure to toxins
  • Diet high in saturated fats
  • Physical inactivity

Diagnosis typically includes:

To confirm coronary arteriosclerosis, a practitioner may use:

  • Thorough medical history and physical examination
  • Blood tests (e.g., lipid panel)
  • Electrocardiogram (ECG) or stress test
  • Coronary angiography or cardiac imaging

These tools help assess atherosclerosis of coronary artery and its effect on heart function.

Management involves:

Treatment focuses on slowing disease progression and improving blood flow. It includes:

  • Lifestyle changes: Heart-healthy diet, regular exercise, and avoiding exposure to environmental tobacco
  • Medications: Statins, ACE inhibitors, beta-blockers, and anti-anginal agents
  • Procedures: Coronary artery bypass, angioplasty, or stenting in advanced cases

Synonyms include

  • Coronary artery disease
  • Coronary atherosclerosis
  • Atherosclerosis heart disease
  • Atherosclerosis of the coronary artery
  • Atherosclerotic heart disease

Commonly asked questions

Use an atherosclerosis coronary ICD-10 code when a patient is diagnosed with atherosclerotic heart disease affecting the coronary arteries, with or without symptoms like angina. Accurate documentation of vessel type (native, graft, or transplanted) and angina status is essential for correct coding.

Yes, all coronary arteriosclerosis diagnosis codes listed in the ICD-10-CM are billable and valid for use in 2025. Providers must select the most specific code that matches the patient's condition for appropriate reimbursement and care documentation.

Common treatments include lifestyle modifications, cholesterol-lowering medications, and antihypertensives to manage disease progression. In severe cases, interventional procedures such as angioplasty or coronary artery bypass graft (CABG) may be necessary.

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