CPT Code 38241: Hematopoietic Progenitor Cell (HPC); Autologous Transplantation

CPT code 38241 is specifically used to bill for autologous hematopoietic progenitor cell transplantation, which involves the reinfusion of a patient’s own stem cells collected previously for transplantation purposes. It is appropriate and intended for autologous transplants only, not for allogeneic or other types of transplants.

You can bill 38241 more than once only if multiple distinct autologous transplant procedures occur on separate occasions, but not multiple times for the same transplant session; repeat procedures require appropriate modifiers and documentation to support medical necessity and distinct services.

Services not included in 38241 typically encompass the harvesting or collection of the stem cells (reported separately with codes like 38206 or 38232), preparatory procedures such as cryopreservation or thawing, and post-transplant care or monitoring; these must be billed with their respective codes and are not bundled into 38241.