Anemia of Chronic Disease ICD-10-CM Codes

Anemia of Chronic Disease ICD-10-CM Codes

By Patricia Buenaventura on Jul 16, 2025.

What ICD-10 Codes are used for Anemia of Chronic Disease?

Anemia of Chronic Disease, often known as Anemia of Inflammation, has several associated ICD-10 codes. Here are the most commonly used ones for conditions like sickle cell anemia, anemia of chronic kidney disease, etc.:

D63.1: Anemia in chronic kidney disease

This code is used when the anemia is directly linked to chronic kidney disease.

D63.8: Anemia in other chronic diseases classified elsewhere

This code is utilized for conditions like anemia associated with chronic heart disease.

D63.0: Anemia in neoplastic disease

This code is for anemia related to cancerous conditions.

D64.9: Anemia, unspecified

This is a general code used when the exact type of anemia is unknown.

D64.81: Anemia due to antineoplastic chemotherapy

This code indicates anemia caused by chemotherapy for cancer treatment.

Which Anemia of Chronic Disease ICD codes are billable?

Here's a look at the billability of the codes we've just discussed:

  • D63.1: Yes, this is a billable code. It indicates anemia in chronic kidney disease.
  • D63.8: Yes, this code is billable. It's used for anemia related to chronic diseases not classified elsewhere.
  • D63.0: Yes, this is billable. It's used for anemia in neoplastic diseases.
  • D64.9: Yes, this is a billable code. It represents unspecified anemia.
  • D64.81: Yes, it is billable. It's for anemia due to antineoplastic chemotherapy.

Clinical information

  • Anemia of chronic disease is a form of anemia in individuals with disorders involving the immune system or blood, like sickle cell disease or chronic illnesses such as cancer, autoimmune diseases, and chronic infections.
  • This condition disrupts iron metabolism and reduces erythropoietin production, a hormone stimulating red blood cell production, leading to anemia.
  • Symptoms vary widely and are often related to the underlying disease. Common indications include fatigue, weakness, and pallor. In some cases, anemia is detected during routine blood tests.
  • Diagnosis typically involves blood tests to measure hemoglobin levels and other markers. This type of anemia often indicates an underlying chronic illness requiring further investigation.
  • Treatment primarily focuses on managing the underlying disease. For severe anemia, treatments may include iron supplementation or erythropoiesis-stimulating agents.
  • The prognosis for Anemia of Chronic Disease is generally tied to the underlying condition's outcome. Effective management of chronic disease often leads to anemia improvement.
  • ICD-10 codes for this condition are crucial for accurately documenting in medical records, ensuring appropriate healthcare services reimbursement, and conducting epidemiological research.

Synonyms include

  • Anemia of inflammation
  • Chronic illness-related anemia
  • Anemia in chronic illness
  • Anemia due to chronic disease
  • Anemia in long-term conditions

Related ICDs

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