Endometrial Thickening ICD-10-CM Codes

Yes, endometrial thickening—especially when classified as complex hyperplasia with atypia—can increase the risk of developing endometrial cancer. The presence of atypical cells is a key indicator of potential progression to malignancy and requires close monitoring or treatment.

Endometrial thickening is typically diagnosed using a transvaginal ultrasound to measure the thickness of the uterine lining. If abnormalities are found, an endometrial biopsy is often performed to determine if hyperplasia or atypia is present.

Treatment depends on the type of hyperplasia and whether atypia is present, but may include hormonal therapy such as progestins, regular monitoring, or surgery. In severe or precancerous cases, a hysterectomy may be recommended to eliminate the risk of progression to cancer.