HCPCS Code E0465: Home Ventilator, Any Type, Used with Invasive Interface

E0465 is for home ventilators used with an invasive interface like a tracheostomy tube, while E0466 is for ventilators used with noninvasive interfaces such as masks or chest shells.

Medicare does cover HCPCS code E0465, which is for home ventilators used with an invasive interface such as a tracheostomy tube. Coverage is specifically for treatment of conditions including chronic respiratory failure consequent to chronic obstructive pulmonary disease (COPD), neuromuscular diseases, and thoracic restrictive diseases, supported by appropriate ICD-10-CM diagnosis codes.

E0466 is the HCPCS code for home ventilators used with non-invasive ventilation interfaces.

J2469 is the HCPCS code for granisetron hydrochloride injection, per 1 mg. Billing requires specification of dose and formulation per CMS and AAPC drug coding guidelines.