F33.3 – Major depressive disorder, recurrent, severe with psychotic symptoms

F33.3 – Major depressive disorder, recurrent, severe with psychotic symptoms

By Karina Jimenea on Jul 16, 2025.

F33.3 diagnosis code: Major depressive disorder, recurrent, severe with psychotic symptoms

The F33.3 diagnosis code refers to major depressive disorder that is recurrent, meaning your client has had multiple episodes, not just a one-time experience. The "severe with psychotic symptoms" part means their depression is intense and includes features like delusions or hallucinations, which may not always be mood-congruent psychotic symptoms.

As a professional, you’ll want to closely monitor for safety risks and ensure coordinated care, as this level of severity often requires both medication and therapy.

Is F33.3 billable?

Yes, F33.3 is a billable code that can indicate a diagnosis of major depressive disorder, recurrent, severe, with psychotic symptoms for reimbursement purposes. The code is valid for submission on a claim form and accurately represents the patient's condition.

Clinical information

  • It affects individuals of all ages, although it is more common in adults.
  • The exact cause of major depressive disorder is unknown but involves a combination of genetic, biochemical, environmental, and psychological factors.
  • Stressful life events may trigger a depressive episode, increasing the risk of developing recurrent episodes.
  • Treatment involves a combination of psychotherapy, antidepressant medications, and antipsychotic medications to manage symptoms and prevent relapses.
  • Early intervention and ongoing symptom monitoring are crucial for improving the patient’s quality of life, especially when the condition co-occurs with other behavioral disorders.

Synonyms include

  • Recurrent severe depression with psychosis
  • Recurrent severe episodes of psychotic depression
  • Severe recurrent depressive disorder with psychotic features
  • Recurrent major depression with psychotic symptoms
  • Severe depressive episode with psychotic features, recurrent
  • Psychotic major depressive disorder, recurrent

Other ICD-10 codes commonly used for major depressive disorder

Related ICDs

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