Q4205 is a HCPCS Q-code that reports a membrane graft or membrane wrap per square centimeter of product applied. It is billed by area in sq. cm. and must be submitted with the appropriate application CPT code that describes how and where the graft or wrap was used.

HCPCS Code Q4205: Membrane Graft or Membrane Wrap
Get paid for every claim. Our billing guide for HCPCS code Q4205 gives you the essential documentation, units, and modifier tips you need to avoid denials.
Frequently asked questions
Yes, Q4205 can be covered when medical necessity is met and when the claim follows CMS and MAC guidelines, including precise units, linked application codes, and complete invoice information. Final payment depends on local Medicare contractor processing, payment allowance limits, and policy review of documentation.
There is no single Q-code for all skin substitutes. CMS assigns product-specific Q-codes across a range, and some items fall under general descriptors. Use the correct Q-code for the product, include invoice information, and pair it with the proper application code on the claim.
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