Lupron Depot (leuprolide depot) is used for androgen deprivation in prostate cancer and for gynecologic indications such as endometriosis and uterine fibroids, according to prescribing information. It is also used in pediatrics for central precocious puberty when specialty criteria are met.

HCPCS Code J9217: Leuprolide Acetate (Depot Suspension), 7.5 mg
Master billing for HCPCS code J9217. Our guide covers documentation, units, wastage, and administration codes for Leuprolide Acetate to ensure accurate claims.
Frequently asked questions
J9217 reports the depot, long-acting suspension at 7.5 mg per unit, and you convert the total dose to units. J9218 reports leuprolide acetate per 1 mg for non-depot formulations. Choose the code that matches the formulation and the dose description in the order.
J9217 is an HCPCS drug code, not a CPT code, and many plans require prior authorization for antineoplastic hormone therapy. Medicare Advantage and commercial payers may set step-therapy or coverage criteria tied to diagnosis. Attach supporting documentation to the claim.
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