HCPCS Code J2997: Injection, Alteplase Recombinant, 1 mg

Use HCPCS code J2997 to report the administration of 1 mg alteplase for clot dissolution in acute care or catheter clearance. Ensure appropriate service equipment is used.

Use Code

Frequently asked questions

J2997 is used for billing alteplase, a thrombolytic drug that breaks down clots in cases like stroke, PE, MI, or blocked catheters. It’s billed per 1 mg administered.

Yes. Low-dose alteplase is often used to restore patency to occluded central venous catheters. In these cases, J2997 still applies per 1 mg.

Ensure your documentation includes diagnosis, total dose, administration route, and supporting clinical notes. Include the NDC and lot number if required by your MAC.