## **What is the HCPCS code J2350 for?**
The HCPCS code J2350 is a J code. J codes are HCPCS codes that mostly designate injected medication. In the case of J2350, what's being injected is ocrelizumab, specifically a 1 mg total dosage. Ocrelizumab, which is sometimes called an Ocrevus injection, is an intravenous injection used to treat various types of multiple sclerosis, such as clinically isolated syndrome, active secondary progressive disease, relapsing-remitting MS (RRMS), and primary progressive multiple sclerosis (PPMS).
What this medicine specifically does is to reduce the activity of the patient's immune system to prevent it from attacking the nervous system. This, in turn, reduces the flare-ups of MS and slows down physical disability progression caused by MS.
This should only be used if the patient has been confirmed to have had inadequate responses to other forms of treatment.
## **Documentation requirements for J2350**
As with any procedure, especially involving injecting drugs into patients, it's important to document the following before you file for a claim that includes this code:
- The full name of the personnel who administered the injection + their credentials
- The name and address of the facility where the injection was administered
- The physician's order for this injection
- The full name of the patient
- The date and time of the drug administration by injection, including the NDC number of the injection
- Patient records showing they have been diagnosed with a type of multiple sclerosis (e.g., primary progressive MS, relapse-remitting MS, etc.)
- Patient records showing any other active disease
- Patient records showing if they have an active infection
- Patient records showing if the patient had clinical relapses of MS
- Hepatitis B virus screening results (if this is the first dose; not needed for subsequent doses)
- Any functional assessment results (e.g., expanded disability status scale results)
- Blood test results and imaging test results of the spinal cord showing multiple sclerosis
- The exact dosage and route
## **Billing requirements for J2350**
Besides the documentation requirements above, please note the following billing requirements for this HCPCS code:
- They must reflect the dosage given over the course of the treatment.
- Use either of two modifiers: JW if there's unused medication in a vial (wastage), or JZ if there's no unused medication.
Please make sure to use the proper ICD code based on your patient's multiple sclerosis, as well as the CPT code 96365, since this is for an intravenous injection.
Please make sure to follow mandates for CMS, Medicare, or Medicaid services to ensure smooth billing and avoid claim rejections.
## **Other similar codes**
- **J3262** - Injection, tocilizumab, 1 mg
- **J3380** - Injection, vedolizumab, 1 mg
- **J2357** - Injection, omalizumab, 5 mg
- **J2323** - Injection, natalizumab, 1 mg
Frequently asked questions
