CPT Code 64450: Under Introduction/Injection of Anesthetic Agent (Nerve Block), Diagnostic or Therapeutic Procedures on the Somatic Nerves

Learn about the 64450 CPT code and its billing implications. Ensure accurate coding and improve your billing and documentation by reading this article.

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Frequently asked questions

No. Imaging guidance, such as ultrasound, is not included in CPT 64450. If ultrasound guidance is medically necessary and properly documented, bill separately with CPT code 76942.

No. CPT 64450 is specifically for peripheral nerve or branch injections not covered by other codes. Sympathetic nerve blocks have separate, dedicated CPT codes and should not be reported with 64450.

You can bill CPT 64450 once per distinct peripheral nerve or branch injected per session. If multiple separate nerves are injected during the same encounter, use Modifier 59 for each additional nerve to clearly differentiate services.