What is esophagogastroduodenoscopy (EGD) with biopsy (CPT 43239)?
CPT code 43239 refers to an esophagogastroduodenoscopy (EGD) with biopsy, a procedure performed to visually inspect the upper gastrointestinal tract, including the esophagus, stomach, and duodenum (the first portion of the small intestine). During this EGD procedure, a healthcare provider uses a flexible endoscope to examine these areas and collect tissue samples using biopsy forceps. This process helps diagnose conditions like gastritis, gastrointestinal diseases, ulcers, abnormal growths, or malignancies.
The procedure performed under CPT code 43239 is considered diagnostic. It may be indicated for a variety of reasons, such as unexplained upper abdominal pain, bleeding, difficulty swallowing, or suspicion of cancer. Collecting biopsies during the examination allows further investigation into the cause of symptoms and supports informed clinical decision-making.
Because this is a separate procedure that includes biopsy, code 43239 is used only when a biopsy is taken during the upper gastrointestinal endoscopy. It should not be billed alongside 43235, which describes an EGD without biopsy. Understanding the appropriate use of this CPT code is essential for accurate billing, proper code selection, and compliant coding practices.






