Angioedema ICD-10-CM Codes
Learn about the different angioedema ICD-10-CM codes you can use through this guide.

What ICD-10 codes are used for angioedema?
Angioedema is a medical condition characterized by swelling beneath the skin, usually around the eyes and lips. Here are some commonly used angioedema ICD codes:
- T78.3XXA: Angioneurotic edema, initial encounter. This code documents an initial encounter with a patient with angioedema due to an allergic reaction.
- T78.3XXD: Angioneurotic edema, subsequent encounter. This code applies to follow-up visits for patients dealing with allergic angioedema.
- T78.3XXS: Angioneurotic edema, sequela. This code is used for complications or conditions that directly result from allergic angioedema.
- T78.2XXA: Anaphylactic shock, unspecified, initial encounter. Used when a patient presents with an unspecified form of anaphylactic shock for the first time.
- T78.2XXD: Anaphylactic shock, unspecified, subsequent encounter. This code is for follow-up visits for patients with an unspecified form of anaphylactic shock.
- T78.2XXS: Anaphylactic shock, unspecified, sequela. Used for conditions that result directly from an unspecified form of anaphylactic shock.
Which angioedema ICD codes are billable?
Here is a summary of whether the ICD codes mentioned above are billable:
- T78.3XXA: Yes, this code is billable and used for the initial encounter with an allergic angioedema patient.
- T78.3XXD: Yes, this billable code applies to follow-up visits for patients dealing with allergic Angioedema.
- T78.3XXS: Yes, this billable code is used for complications arising from allergic Angioedema.
- T78.2XXA: Yes, this billable code is used for the initial encounter with an unspecified form of anaphylactic shock.
- T78.2XXD: Yes, this code is billable and used for follow-up visits for patients dealing with an unspecified form of anaphylactic shock.
- T78.2XXS: Yes, this billable code is used for conditions resulting from an unspecified form of anaphylactic shock.
Clinical information
Angioedema is a rapid, localized skin swelling that often affects deeper layers of the skin and mucosa. The swelling is usually non-itchy but can be painful. Here are some essential points:
- Angioedema can occur due to an allergic reaction or non-allergic causes.
- It often affects areas with loose tissues, such as the face, throat, and limbs.
- It may be accompanied by urticaria (hives), which is treated by serum urticaria therapy (autologous serum therapy).
- The condition can have adverse effects and become life-threatening if it causes airway obstruction.
- While this can be idiopathic, it can be caused by external causes, like latex, venomous insect bites, taking medication, or food that a person is allergic to.
- Depending on where the angioedema is located, it could lead to certain other consequences if left unaddressed, such as asphyxia, difficulty breathing, and death.
- Treatments include avoiding triggers, antihistamines, and steroids.
- Genetic angioedema is a hereditary condition requiring different treatment approaches.
Synonyms include
- Angioneurotic edema
- Allergic angioedema
- Anaphylactic shock
- Non-allergic angioedema
- Hereditary angioedema
- Acute angioedema
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Commonly asked questions
Angioedema can be triggered by allergens, such as certain foods, medications, insect bites, or physical factors like heat or pressure.
While angioedema can often be mild and short-lived, it can be severe if the swelling causes airway obstruction, leading to breathing difficulties.
Treatment often involves antihistamines, corticosteroids, or other medications to reduce swelling and pain. Avoidance of known triggers is also essential.