Cold Agglutinin

Cold agglutinins can be associated with autoimmune disorders (e.g., rheumatoid arthritis), infections (e.g., Mycoplasma pneumoniae), or lymphoproliferative disorders.

The test is generally safe, but like any blood draw, there may be minor risks such as bruising or infection at the collection site. These risks are minimal and rare.

Treatment depends on the underlying cause and severity of symptoms. It may include avoiding cold exposure, addressing the underlying condition, and, in severe cases, medications or blood transfusions.