HCPCS Code J9228: Injection Ipilimumab, 1 mg

HCPCS Code J9228 is used for ipilimumab treatment in cancers such as unresectable or metastatic melanoma, renal cell carcinoma, non-small cell lung cancer, and malignant pleural mesothelioma.

Yes. J9228 may be billed when ipilimumab is administered alongside other agents, such as nivolumab, provided documentation supports medical necessity.

Common reactions include immune-mediated colitis, hepatitis, pneumonitis, endocrinopathies, and infusion-related reactions, which should be recorded in the patient’s chart.