Hypophosphatemia ICD-10-CM Codes | 2025

Hypophosphatemia ICD-10-CM Codes | 2025

Read this short guide to learn about Hypophosphatemia ICD codes you can use.

By Matt Olivares on Aug 8, 2025.

Fact Checked by Karina Jimenea.

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What hypophosphatemia ICD-10 codes can I use?

If you're looking for Hypophosphatemia ICD codes, there are two that you can use. Here they are:

E83.31 - Familial hypophosphatemia

This ICD-10 code is meant to be used on a patient confirmed to have familial hypophosphatemia. Familial hypophosphatemia is the umbrella term for rare genetic medical disorders that impact the kidney's ability to conserve phosphate, leading to lower levels of phosphate in the blood.

Medical problems under this umbrella include autosomal dominant hypophosphatemic bone disease and autosomal dominant hypophosphatemic rickets.

If your patient's hypophosphatemia results from genetics, you can use this code.

E83.39 - Other disorders of phosphorus metabolism

This ICD-10 code is meant to be used on a patient confirmed to have hypophosphatemia, a type of hypophosphatemia that isn't genetic. Hypophosphatemia can be caused by long-term use of diuretics, Vitamin D deficiency, electrolyte disorders, and theophylline intoxication, to mention a few.

Are both these hypophosphatemia ICD-10 codes billable?

Yes. Both ICD-10 codes for hypophosphatemia are valid and billable.

Clinical information about hypophosphatemia

Before we discuss hypophosphatemia, let's briefly discuss phosphates. To put it simply, phosphates are essential minerals that our body needs. They allow the building of our bones and teeth, repair them if they suffer damage, and help ensure that our nerves function well and our muscles contract.

Hypophosphatemia is a metabolic disease characterized by an abnormal phosphate deficiency in the bloodstream. This can be caused by several problems, from alcohol abuse and withdrawal to ketoacidosis.

A person with this metabolic disorder will likely have the following symptoms:

  • They will probably become irritable and confused
  • They will feel numbness all over their body
  • Their muscles will feel weak and painful
  • They might feel pain in their bones
  • They might suffer seizures

Synonyms include

  • Autosomal dominant hypophosphatemic bone disease
  • Autosomal dominant hypophosphatemic rickets
  • Dominant hypophosphatemia with nephrolithiasis and/or osteoporosis
  • Dysplasia with defective mineralization
  • Hereditary hypophosphatemic rickets with hypercalciuria
  • Acid phosphatase deficiency
  • Acquired hypophosphatemia
  • Adult hypophosphatasia
  • Childhood hypophosphatasia
  • Hypophosphatemia affecting calcium metabolism
  • Hypophosphatemia affecting iron metabolism

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Commonly asked questions

It can lead to a person developing arrhythmia and heart failure. It can also cause metabolic encephalopathy. It’s also possible for people with hypophosphatemia to lapse into a coma or die, so it’s best to get it treated as soon as possible.

They will conduct blood tests to check the bloodstream's phosphate, calcium, and Vitamin D counts. They might also perform kidney function tests, urinalysis, and imaging tests to confirm or rule out other patient problems.

It depends on the severity, but the core treatment revolves around stabilizing the phosphate count in the bloodstream. For mild cases, this can be done by consuming phosphate replacement medication, and for severe cases, phosphate replacement via IV might be suggested. Dietary changes might also be suggested. 

Related ICDs

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