Family History Breast Cancer ICD-10-CM Codes | 2025

Family History Breast Cancer ICD-10-CM Codes | 2025

Explore 2025 ICD-10-CM codes for family history of breast cancer, genetic susceptibility, and billing guidance to support accurate clinical documentation.

By Wynona Jugueta on Aug 8, 2025.

Fact Checked by Gale Alagos.

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Commonly asked questions

No, Z80.41 specifically refers to a family history of ovarian cancer and should not be used to indicate a history of breast cancer. While breast and ovarian cancers may share genetic risk factors, such as BRCA mutations, they each require distinct ICD-10-CM codes for accurate documentation.

No, Z86.010 is designated for a bilateral prophylactic mastectomy and should only be used when both breasts have been removed to reduce cancer risk. For a unilateral prophylactic mastectomy, no specific ICD-10-CM code exists, so documentation should be detailed in clinical notes.

Z15.02 should only be used when a confirmed genetic susceptibility to breast cancer is documented, such as a positive BRCA1 or BRCA2 test result. It is not appropriate for use during the testing phase—only after results have verified genetic risk.

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