F33 – Major depressive disorder, recurrent

F33 – Major depressive disorder, recurrent

Explore the ICD-10-CM code F33 for major depressive disorder, recurrent. Learn about clinical descriptions, billability, related codes, synonyms, FAQs, & more.

By Chloe Smith on Jul 16, 2025.

Fact Checked by RJ Gumban.

Use Code

F33 Diagnosis Code: Major Depressive Disorder, Recurrent

  • Characterized by multiple episodes of major depression.
  • Episodes are separated by periods of remission lasting at least two months.
  • Symptoms include persistent sadness, loss of interest, changes in appetite and sleep patterns, fatigue, and feelings of worthlessness or guilt.
  • Patients may experience difficulty concentrating, making decisions, and engaging in daily activities.
  • Suicidal thoughts or behaviors may be present in severe cases.
  • Requires diagnosis by a mental health professional.

Is F33 Billable?

Yes, F33 is a billable code that can indicate a diagnosis of major depressive disorder, recurrent for reimbursement purposes. The code is valid for submission on a claim form and accurately represents the patient's condition.

Clinical Information

  • It affects individuals of all ages, although onset typically occurs during late adolescence or early adulthood.
  • Risk factors include family history, personal history of depression, chronic medical conditions, substance abuse, and traumatic life events.
  • The exact cause remains unknown but involves genetic, biochemical, environmental, and psychological factors.
  • Treatment may include a combination of psychotherapy, medication, and lifestyle changes.
  • Early intervention and ongoing monitoring of symptoms are crucial for preventing relapses and improving quality of life.

Synonyms Include

  • Recurrent major depression
  • Recurrent depressive disorder
  • Major depression, recurrent
  • Periodic depressive disorder
  • Repeated episodes of major depressive disorder

Other ICD-10 Codes Commonly Used for Depression

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