Cluster Headache Treatment Guidelines Handout

The first line of a management of cluster headache typically includes acute medications such as triptans (like sumatriptan) and high-flow oxygen therapy to relieve pain quickly and effectively.

An intractable cluster headache can last from 15 minutes to 3 hours, occurring up to multiple times a day during a cluster period, which can last weeks to months.

In the emergency room, cluster headache treatment may involve administering oxygen therapy, intravenous medications like dihydroergotamine or corticosteroids, and assessing for any complications or need for further intervention.