HCPCS G0482: Drug test(s), definitive, 15–21 drug classes

Not necessarily. Some payers require a presumptive screen first, while others allow direct definitive testing when clinically justified. Documentation should support either approach.

Yes, but only one definitively billed G-code and one presumptively billed CPT code are permitted per patient per date of service. Each code encompasses specimen validity testing.

G0482 is for definitive drug testing, which can be either qualitative (identifies presence/absence) or quantitative (identifies concentration), as specified in the long description.