HCPCS code J9271: Injection, Pembrolizumab, 1 mg

You would bill J9271 × 200 units, as each unit equals 1 mg.

Yes. Use JW to indicate any drug wastage, and JZ when the entire vial is administered with no waste. For single-use vials like Keytruda, JZ is mandatory when no discard occurs.

Coverage depends on the payer and other guidelines, such as indication-specific policies. Examples include: MSI-high/dMMR tumors, NSCLC, melanoma, head/neck cancers, urothelial carcinoma, Hodgkin lymphoma, and others as outlined in UnitedHealthcare coverage tables. Claims must include appropriate additional codes (ICD-10) based on diagnosis.