HCPCS Code J2353: Injection, Octreotide, 1 mg

Octreotide is a synthetic analog of somatostatin, classified as a somatostatin receptor agonist, which inhibits the release of several hormones and substances such as growth hormone, insulin, and gastrointestinal peptides.

In gastrointestinal (GI) surgery, octreotide is used to reduce complications by decreasing the secretion of digestive fluids, managing conditions like pancreatic fistulas, bleeding varices, and certain types of tumors, thereby improving postoperative outcomes.

Octreotide is generally covered by Medicare when prescribed for approved medical conditions such as acromegaly, certain tumors, or severe diarrhea related to carcinoid syndrome, but coverage details may vary based on specific plan rules and indications.