Typically, for chronic migraine, CMS and payer guidelines accept 100 units per treatment (injected across multiple sites). Bill 100 units of J0585, document site-specific injections, and use the appropriate administration code (generally 64615 for bilateral chemodenervation).

HCPCS code J0585: Injection, OnabotulinumtoxinA, 1 unit
Gather more information on the documentation and billing requirements needed to properly use and bill HCPCS code J0585 from our short guide.
Use Code
Frequently asked questions
Yes. These are required when applicable for single-use vials. Use JW to indicate drug waste and JZ when there is no waste—documentation must reflect these details.
If J0585 is denied, the associated CPT injection code (e.g., 64612 or 64615) will also likely be denied, as they must be billed together.
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