HCPCS Code J0490: Injection, belimumab, 10 mg

Optimize billing for HCPCS J0490. This guide covers units, documentation, and modifiers for belimumab infusions to ensure accurate payment.

Use Code

Frequently asked questions

J0490 reports injection, belimumab, 10 mg for systemic lupus erythematosus and active lupus nephritis, allowing unit-accurate billing based on dose administered.

Benlysta (belimumab) is a biologic drug that targets BLyS to reduce autoantibody activity, supporting treatment of autoantibody-positive lupus and lupus nephritis when added to standard therapy.

Weight change is not a typical signal; safety concerns focus on infection risk, hypersensitivity, depression/suicidality, and infusion reactions. Providers should monitor and counsel patients per label and payer policy; Medicare and commercial plans may require ongoing documentation of benefits and tolerability supported by clinical data.