HCPCS Code J0174: Injection, lecanemab-irmb, 1 mg

Leqembi is administered as an intravenous infusion in a clinical setting, often every two weeks. Each billing unit under HCPCS code J0174 represents 1 mg of the drug, so providers must report the exact dosage given during the session.

Baseline MRI scans help detect any pre-existing brain changes or risks, such as amyloid-related imaging abnormalities with hemosiderin deposition (ARIA-H). This ensures patient safety before the first infusion and guides monitoring during treatment.

Yes, but only if they meet Medicare’s National Coverage Determination (NCD 200.3) criteria, which currently limits coverage to certain CMS-approved studies or qualifying clinical research. Providers must document how the patient meets these requirements and include the study or registry number on the claim.