R68.89 - Other general symptoms and signs

No, it cannot be a primary diagnosis since it's only meant to be used for signs and symptoms.

It should be used when the healthcare provider discovers a symptom but doesn't have any definitive diagnosis yet.

The most important guidelines is to always code to the highest level of specificity. This is to say that if a more specific diagnosis can be established, then a healthcare provider must avoid using R68.89.